Gabriel Koch Ocker

Scientist II, Allen Institute for Brain Science
PhD, Neuroscience, University of Pittsburgh
BA, Applied Math & Neuroscience, Oberlin College

I work on models and theoretical approaches for linking the structure and activity, and the learning and computation, of spiking networks and on understanding sensory coding, particularly in the mouse visual system.

For code related to publications, check my github.


Ocker GK, Buice MA. Flexible neural connectivity under constraints on total connection strength. on bioRxiv. preprint

Millman DJ, Ocker GK, Caldejon S, Kato I, Lee E, Luviano J, Nayan C, Nguyen TV, North K, Seid S, White C, Lecoq J, Reid RC, Buice MA, de Vries SEJ. VIP interneurons selectively enhance weak but behaviorally-relevant stimuli. on bioRxiv. preprint

Siegle JH*, Jia X*, Durand S, Gale S, Bennett C, Graddis N, Heller G, Ramirez T, Choi H, Mihalas S, Luviano JA, Groblewski P, Ahmed R, Arkhipov A, Bernard A, Billeh Y, Brown D, Buice MA, Cain N, Caldejon S, Casal L, Cho A, Chvilicek M, Cox T, Dai K, Denman D, de Vries SEJ, Dietzman R, Esposito L, Farrell C, Feng D, Galbraith J, Garrett M, Gelfand EC, Hancock N, Howard R, Hu B, Hynten R, Iyer R, Jessett E, Johnson K, Kato I, Kiggins J, Lambert S, Lecoq J, Ledochowitsch P, Lee JH, Leon A, Li Y, Liang E, Long F, Mace K, Melchio J, Mollenkopf T, Nayan C, Ng L, Ngo K, Nguyen T, Nicovich R, North K, Ocker GK, Ollerenshaw D, Oliver M, Pachitariu M, Perkins J, Reding M, Reid D, Robertson M, Ronellenfitch K, Seid S, Slaughterbeck C, Stoecklin M, Sullivan D, Sutton B, Swapp J, Thompson C, Turner K, Wakeman W, Williams D, Williford A, Young R, Zeng H, Naylor S, Phillips JW, Reid RC, Olsen SR*, Koch C*. A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas. on bioRxiv. preprint (*: equal contribution)

de Vries SEJ*, Lecoq J*, Buice MA*, Groblewski PA, Ocker GK, Oliver M, Feng D, Cain N, Ledochowitsch P, Millman D, Roll K, Garrett M, Keenan T, Kuan L, Mihalas S, Olsen S, Thompson C, Wakeman W, Waters J, Williams D, Barber C, Berbesque N, Blanchard B, Bowles N, Caldejon S, Casal L, Cho A, Cross S, Dang C, Dolbeare T, Edwards M, Galbraith J, Gaudreault N, Griffin F, Hargrave P, Howard R, Huang L, Jewell S, Keller N, Knoblich U, Larkin J, Larsen R, Lau C, Lee E, Lee F, Leon A, Li L, Long F, Luviano J, Mace K, Nguyen T, Perkins J, Robertson M, Seid S, Shea-Brown E, Shi J, Sjoquist N, Slaughterbeck C, Sullivan D, Valenza R, White C, Williford A, Witten D, Zhuang J, Zeng H, Farrell C, Ng L, Bernard A, Phillips JW, Reid RC*, Koch C*. (2019) A large-scale, standardized physiological survey reveals higher order coding throughout the mouse visual cortex. Nat. Neurosci. 23: 138-151 article. (*: equal contribution)

Linaro D, Ocker GK, Doiron B, Giugliano M. Correlation transfer by layer 5 cortical neurons under recreated synaptic inputs in vitro. (2019) J. Neurosci. 25 July 2019: 3169-18 article

Recanatesi S, Ocker GK, Buice MA, Shea-Brown E. (2019) Dimensionality in recurrent spiking networks: global trends and local origins in connectivity. PLoS Comp Biol 15(7):e1006446. article

Ocker GK and Doiron B. Training and spontaneous reinforcement of neuronal assemblies by spike timing plasticity. (2018) Cereb. Cortex. (advance online, article

Ocker GK*, Hu Y*, Buice MA, Doiron B, Josić K, Rosenbaum R, Shea-Brown E. (2017) From the statistics of connectivity to the statistics of spike times in neuronal networks. Curr. Opinion Neurobiology 46: 109-1193. (*: equal contribution.) article

Ocker GK, Josić K, Shea-Brown E, Buice MA. (2017) Linking structure and activity in nonlinear spiking networks. PloS Comp Biol 13(6): e1005583. article

Kanashiro T, Ocker GK, Cohen M, Doiron B. (2017) Attentional modulation of neuronal variability in circuit models of cortex. eLife 2017;6:e23978. article

Doiron B, Litwin-Kumar A, Rosenbaum R, Ocker GK, Josic K. (2016). The mechanics of state-dependent neural correlations. Nat. Neurosci. 19(3): 383-393. dos: 10.1038/nn.4242. article

Ocker GK. (2015). Formation of structure in cortical networks through spike timing-dependent plasticity. PhD thesis, University of Pittsburgh. thesis

Ocker GK, Litwin-Kumar A, Doiron B. (2015). Self-organization of microcircuits in networks of spiking neurons with plastic synapses. PLoS Comp Biol 11(8): e1004458. article

Ocker GK, Doiron B. (2014). Kv7 channels regulate pairwise spiking covariability in health and disease. J Neurophysiol. 112:340-352 (2014). article

Coggan JS, Ocker GK, Sejnowski TJ, Prescott SA. (2011). Explaining pathological changes in neuronal excitability through dynamical analysis of conductance-based models. J Neural Eng. 8(6):065002. article